Selling or giving away this medication is dangerous and against the law. Do not share this medication with anyone. Keep your medication in a safe place to protect it from theft. You may report side effects to FDA at FDA-1088. Call your doctor for medical advice about side effects. This list may not describe all possible side effects. This medication is banned from use in athletes by most athletic organizations. Long-term zinc supplementation may lead to increased testosterone levels. Several types of supplements claim to increase your testosterone levels. Some older people on testosterone therapy could face increased cardiac risks. Your healthcare provider will work with you to figure out which option is best for you. Together, you and your healthcare provider will decide if TRT is right for you. Testosterone replacement therapy (TRT) can help improve the symptoms of low testosterone due to male hypogonadism. Estrogens can reduce the effects of testosterone by increasing the hepatic production and in turn circulating levels of sex hormone-binding globulin (SHBG), a carrier protein that binds to and occupies androgens like testosterone and DHT, and thereby reducing free concentrations of these androgens. As only a very small fraction of testosterone is converted into estradiol, this does not affect testosterone levels, but it can prevent estrogenic side effects like gynecomastia that can occur when testosterone is administered at relatively high dosages.