In some cases, this may contribute to mental health challenges such as body dysmorphia or eating disorders. Concerns are growing over the influence bodybuilding content on social media has on young adults and their perception of their own bodies, as they often compare themselves to gym influencers online. Although social media is giving more attention to the world of bodybuilding, there are still some areas that are controversial. The advent of social media had a profound influence on fitness and bodybuilding. However, this effort was unsuccessful, and Olympic recognition for bodybuilding remains controversial, as many argue that it is not truly a sport. In individuals who have this gene, normally located on the Y chromosome, testes development will occur. A collective term for these individuals is "transgender", whilst others will relate to terms such as gender dysphoria (GD) or gender incongruence. It is a general descriptive term referring to an individual’s discontent with the assigned gender.1 In this context, it is important to highlight the difference between sex and gender – two terms which are commonly used interchangeably and yet mean very different things. These point to a possible biological and genetic underpinning of GD as stemming from a discordance between gonadal and brain development. It affects one in 50 people, and despite public perception of body image issues predominantly impacting women, BDD is just as common in males as in females. A focus on brain anatomy highlights a difference between males and females and shows that brain function too is gender-orientated, with, for example, a hypothalamic response to androstadienone which differs significantly between the two sexes. There is a lack of knowledge of the influences of sexual identity on neuronal function.44–46 There has been little research on people identifying as transgender and how their brain structure differs from those whose sex and gender are matched.